Tag: Hemp

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CBD Softgel Capsules: Benefits, Uses, and Why They’re a Convenient Choice for Daily Wellness

What Is CBD?
Cannabis plants like hemp and marijuana contain organic compounds we refer to as cannabinoids. Among these cannabinoids, the two we most commonly encounter are CBD and THC. Products derived from these plants are often associated with a “high,” or feeling of euphoria, which can be attributed to the THC compound.

When it comes to controlled medicinal uses, however, the CBD compound is used. Because the CBD compound contains almost no THC, it does not cause the psychoactive responses that make you feel high.

What Are the Benefits of CBD in Supplements?
As supplements, most forms of CBD are not evaluated by the FDA. However, research has been done regarding the benefits of CBD use. Keep in mind that although there may be scientific evidence to support positive health benefits, results may vary and medical guidance is recommended.

People who use CBD do so because they believe it:

Provides mood support
May support nervous system health
May support heart and circulatory health

What Are CBD Capsules?
CBD capsules offer a highly convenient way to consume CBD extract. They contain CBD in various concentrations, all in a small, discreet form. CBD capsules are often preferred by people who want to modulate their dose of CBD without the hassle of measuring CBD oil or applying a topical product. These capsules are a great option for those who dislike the taste or aroma of CBD oil.

Just like any other supplement or pill, CBD capsules are taken orally and absorbed in the digestive tract. For many, the simplicity of CBD capsules makes it easier to begin, or remain consistent with, a daily CBD regimen.

What Are CBD Capsules Used For?
CBD capsules are used for a variety of potential health benefits. Some common uses for CBD capsules include:

Stress relief and relaxation
Sleep support
Mood regulation
Anti-inflammatory support
Overall wellness

Individual responses to any supplement varies, but many people report positive effects from using CBD capsules to support their health and well-being.

How CBD capsules are taken also varies from person to person. They typically come in two forms: hard capsules and soft gel capsules.

What Are CBD Softgel Capsules?
CBD softgel capsules are small, consumable pills with casings made from gelatin or other dissolvable materials and a filling of CBD diluted in a carrier oil. Among all the forms available on the market, CBD softgels are among the most effective for ingesting CBD. Their simplicity and easy integration into daily routines makes them a popular choice among a wide range of people.

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Formula
Featuring a filling of concentrated CBD oil, CBD softgel capsules appeal to those seeking to take CBD for various purposes. The creation process of the concentrated oil includes extracting CBD compounds using CO2. The extracted oil combines with medium-chain triglycerides (MCT), hemp, coconut, vegetable, or another carrier oil.

Some formulas may also contain emulsifiers and other fatty acids, providing additional benefits, such as digestion and absorption support, or supplement appearance and stability.

Strength
CBD softgels make proper dosing easier because of the accurate measuring of the formula in each capsule. Ultimately, the strength of each dose depends on the needs of the individual. CBD softgel capsules come in low or high concentrations to help individuals find the dosage strength that provides maximum benefits.

Side Effects
As with any form of CBD, taking CBD softgel capsules comes with a low risk of side effects. These can include dry mouth, light-headedness, drowsiness, nausea, and interaction with other medications. However, CBD consumption is generally considered very safe.

Benefits
Studies have shown that a CBD softgel can potentially benefit people with anxiety, insomnia, chronic pain, and inflammation. CBD can also play a role in mood regulation. CBD softgel capsules have other benefits, including the following:

High efficacy rates
Ease of use
Clear dosage
Neutral taste
Targeted delivery of cannabinoids

Taking CBD in softgel form makes it easier to consume CBD quickly, and the body easily absorbs the water-soluble properties of softgel capsules.

What Are the Pros and Cons of CBD Softgel Capsules?
CBD softgel capsules are a popular way to consume CBD, but there are a few downsides.
Here are some of the pros and cons of CBD softgels:

Pros:
Convenient—Users can take CBD softgel caps anytime, anywhere. They’re discreet, easily stored in an airtight medication container, and involve no mess or extra steps for consumption.
Precise Dosage—CBD softgel capsules contain carefully pre-measured amounts of cannabinoids, so there is no need to measure or guess the dosage.
Tasteless—Unlike many other CBD products, CBD softgels have no bitter taste. In most cases, they have no taste, and users swallow them with water.

Cons:
General Effects—Because the body absorbs the cannabidiol, CBD softgels may not be ideal for people who would benefit from a product targeting a specific area, as would a topical salve.
Deferred Release—Your body won’t realize the effects of CBD capsules until they reach your stomach. As a result, they may take longer to attain their full effect than other CBD products, such as topical, sublingual, or transdermal methods.

Dosage Limitations—While the precise dosage found in CBD softgel capsules is an upside for many people, some may prefer more flexibility to increase or decrease their dose.

The Duration of Effects from CBD Softgel Capsules
The effects of CBD softgel capsules typically last between two and six hours. How long you experience the effects will ultimately depend on your body’s response, the dosage, and the formula’s efficacy.

CBD Softgel Caps to Improve Sleep
One of the most common uses of CBD softgels is to get a better night’s rest. CBD can help improve sleep quality and support calm at bedtime, making falling and staying asleep at night easier. Many CBD softgel capsules are specially formulated as sleep aids with the addition of sleep-promoting ingredients like melatonin.

What Are the Best CBD Softgel Capsules?
To find the best CBD softgel capsules, look for clearly labeled, third-party-tested formulas made with natural ingredients. High-quality CBD softgels always contain premium ingredients that enhance absorption without solvents or other additives.

Look for products with natural, organic ingredients from reputable sources, products that have been scientifically tested, products that are clearly labeled, and products with high manufacturing standards and quality control.

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Myrcene: The Terpene with Cytotoxic Effects on Cancer Tumors

Myrcene functions as a sedative, an analgesic, a systemic anti-inflammatory, an antibiotic, and a cancer cell antagonist.

Of the 200 aromatic terpenes possible in an individual strain (or cultivar) of cannabis, myrcene is the most common. Also known as β-myrcene, this delicate and naturally occurring molecule conveys an earthy, fruity, and musky aroma (depending on other terpenes present).

Also found in hops, lemongrass, parsley, and wild thyme, myrcene composes an average of 30-65 percent of the essential oils in a particular strain of cannabis. Myrcene is employed in many industries outside of cannabis and hemp, including fragrances, food flavoring, pharmaceuticals, and personal care.

The Details

Myrcene is most common in cannabis strains such as Blackberry Kush, Mango Kush, and White Widow. A 1997 study conducted in Switzerland revealed that myrcene is the most abundant terpene in cannabis, sometimes composing up to 50 percent of the terpene volume in an individual sample of cannabis.

Working both alone and in conjunction with other terpenes and cannabinoids, the terpene functions as a sedative, an analgesic (pain killer), a systemic anti-inflammatory, an antibiotic, and a cancer cell antagonist (meaning it reduces the size of tumors).

The molecule may also offer benefits for those suffering Type 2 diabetes, having demonstrated improved glucose tolerance in obese mice in research studies. When consumed in potent doses, myrcene’s analgesic effects are similar to the pharmaceutical sedative phenobarbital. For those suffering osteoarthritis, this terpene has proven to be a powerful anti-inflammatory.

The percentage of myrcene present in an individual strain of cannabis, as measured in its weight by volume, indicates whether it is categorized as an uplifting sativa strain or a more sedative indica variety. According to leading authorities, including Steep Hill Labs in Berkeley, California, cannabis strains containing more than 0.5 percent myrcene are categorized as an indica or indica-dominant, while those sporting less than 0.5 percent of this terpene are considered a sativa or sativa-dominant strain.

Myrcene is responsible for the age-old urban legend that consumption of mangos before smoking cannabis amplifies the psychoactive effects of its infamous molecular cousin, tetrahydrocannabinol (THC). This legend is actually true; cannabis consumers who eat a fresh mango before smoking or vaporizing flowers — or consuming a concentrate — will cause an increase in the potency of the effects of the THC.

Research on Myrcene

The fact that cannabis is considered a Schedule 1 drug by the federal government of the United States has squelched much research that might otherwise have been conducted into the hundreds of helpful terpenes and cannabinoids present in the plant. However, much research has been conducted into terpenes and cannabinoids, both in the U.S. and outside its borders.

A March 2015 osteoarthritis study published in the journal European Journal of Pharmacology demonstrated that myrcene is a significant anti-inflammatory and anti-catabolic (preventing the breakdown of muscle mass). The study concluded that myrcene slowed and, in some cases, even halted the destruction of cartilage involved in this type of arthritis.

A January 2011 study conducted by cannabis researcher Dr. Ethan Russo entitled “Taming THC: Potential Cannabis Synergy and Phytocannabinoid-terpenoid Entourage Effects” and published in the British Journal of Pharmacology concluded that myrcene diminishes inflammation and that it is “analgesic in mice” and “a recognized sedative…employed to aid sleep.” The study also cited the ability of myrcene to act “as a muscle relaxant in mice” and causes sleep, especially when consumed in strong doses.

SOURCE : https://cannabisaficionado.com/myrcene/

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Delta-8-Tetrahydrocannabinol (Delta-8-THC)

Delta-8-THC is a minor cannabinoid, occurring in cannabis in very small concentrations. Delta-8-THC is also a degraded form of delta-9-THC. When THC is stored for a long period of time, it degrades into delta-8-THC.

What is delta-8-THC?
There are more than 100 cannabinoids present in the cannabis plant. While we have some foundational knowledge about primary cannabinoids like delta-9-THC (more commonly known as THC) and cannabidiol (CBD), we know less about the secondary, or minor, cannabinoids like delta-8-THC.

Delta-8-THC is distinct from THC, the most abundant and intoxicating cannabinoid found in cannabis. Delta-8-THC is an analog of THC and has a similar molecular structure with a few notable differences. While the two share many similar properties, such as reportedly stimulating appetite, reducing nausea, and soothing pain, delta-8-THC tends to exhibit a lower psychotropic potency than THC when inhaled. When ingested, however, delta-8-THC can deliver the same intoxicating effects as THC. So be mindful when trying delta-8-THC edibles for the first time and use the same caution you would with THC edibles.

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Chemical structure
From a chemical or structural perspective, delta-8-THC differs from delta-9-THC due to the location of a critical chemical bond. Both forms of THC contain double bonds in their molecular chain. Delta-8-THC contains that bond on the 8th carbon chain, while delta-9-THC contains the bond on the 9th carbon chain. Although it seems like a subtle difference, it has a major impact on the shape of these molecules. This shape directly determines how well the molecules are able to bind to the body’s endocannabinoid receptors.

Molecular stability
Delta-9-THC is less stable than delta-8-THC. Delta-9-THC is easily oxidized to become cannabinol (CBN) or delta-8-THC. Delta-8-THC is stable, does not oxidize to become CBN, and boasts a prolonged shelf life. Such stability is desirable in a medicinal compound.

Affinity for cannabinoid receptors
Delta-8-THC, when inhaled, binds to the CB1 receptor like delta-9-THC, but its affinity for the receptor is different due to its slightly altered molecular structure and related shape. The CB1 receptor is responsible for mediating most of the psychotropic effects of THC. This differential binding may be responsible for delta-8-THC’s reportedly producing a clearer high with less anxiety than delta-9-THC. It’s also possible that delta-8-THC’s molecular structure affects how it interacts with other receptors and neural pathways.

Effects from consumption
Plenty of clinical and anecdotal evidence points to delta-9-THC having intoxicating effects when consumed via inhalation or ingestion. We know much less about the effects of delta-8-THC. Some say delta-8-THC produces a milder, clearer high than delta-9-THC even at higher doses. However, pharmacologically, delta-8-THC edibles function very similarly to delta-9-THC edibles, with both molecules converting into 11-hydroxy-THC in the liver. Because there is so much we have yet to learn about delta-8-THC, and because the effects are very different depending on whether it’s ingested or inhaled, it’s wise to treat these products with the same caution you would treat THC products.

WARNING: Exercise extra caution when trying delta-8-THC edibles for the first time.

A range of preclinical and clinical studies are uncovering some of the unique properties and therapeutic potential of delta-8-THC.

Pain and inflammation
A 2018 preclinical study published in Cannabis and Cannabinoid Research found that delta-8-THC may help to diminish pain and inflammation in corneal injury in mice. The research found that delta-8-THC, applied topically, assisted in pain reduction, and reduced inflammation through its effects on the CB1 receptors. Another preclinical study on rats reported that delta-8-THC delivers pain relief, but that tolerance to the cannabinoid developed rapidly.

Anxiety
According to the US National Library of Medicine, delta-8-THC displays anxiety-reducing qualities similar to delta-9-THC. Anecdotal reports claim that the consumption of delta-8-THC results in a calm, focused high, but we need more clinical research into its anti-anxiety potential before drawing any conclusions.

Nausea
The nausea-fighting potential of delta-8-THC was reported in a 1995 study published in Life Sciences. The study followed eight pediatric cancer patients over two years and found that no vomiting occurred when patients ingested delta-8-THC before and for 24 hours after cancer treatment. The study reported very few side effects.

Lose of appetite
Delta-8-THC may also help stimulate the appetite. Research conducted on mice and published in 2004 in Pharmacology, Biochemistry and Behavior found that a low dose of delta-8-THC administered to mice over 50 days resulted in a 22% increase in food intake compared with controls. The research also reported that delta-8-THC increased food intake significantly more than delta-9-THC, a known appetite stimulant.

Since it’s a minor cannabinoid, we have much more to learn about delta-8-THC, which necessitates a cautious approach toward using it. Presently, the cannabinoid is generally available in concentrated forms, because cannabis flower usually contains less than 1% delta-8-THC.

To acquire a substantial quantity of this cannabinoid, a significant amount of extraction and refinement must take place. While some delta-8-THC concentrates are isolates, other products may combine delta-8-THC with CBD and/or delta-9-THC for a more full-spectrum effect.

If you’re thinking about consuming delta-8-THC, it’s vital to be aware that a great deal of the current knowledge we have about the cannabinoid is based on animal studies. Research on animals has indicated that delta-8-THC (along with delta-9-THC) resulted in increased blood pressure by temporarily constricting the blood vessels. The rise in blood pressure was then followed by a drop in blood pressure and a slower heart rate.

The effects observed in animals can be very different from the effects observed in humans, as evidenced in a 2018 systematic review published in Pharmaceuticals. For example, while delta-8-THC significantly slowed heart rate in animals, it conversely increased heart rate in humans. The authors of the review concluded that there is limited data about the effects of delta-8-THC, and further studies need to be conducted in human populations to understand how it induces changes in blood flow.

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WARNING: Exercise caution when trying delta-8-THC products for the first time.

You should also be aware that like delta-9-THC, ingested delta-8-THC gets converted to 11-hydroxy-THC in the liver. This results in many people overindulging in edibles without realizing it. This also means hemp-derived delta-8-THC edibles may be just as potent as marijuana-derived edibles. Though sometimes unregulated, delta-8-THC edibles can still lead to a very uncomfortable psychological shift for the unprepared.

Inhaling delta-8-THC won’t send the cannabinoid to your liver, and as a result, won’t produce the same potentially intoxicating effects.

WARNING: Exercise extra caution when trying delta-8-THC for the first time.

SOURCE: WEEDMAPS.COM

Delta 8 Gummy Giveaway!

Statements regarding Delta-8, CBD, hemp, or dietary supplements have not been evaluated by the FDA, and are not intended to diagnose, treat, cure, or prevent any disease or health condition.